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  The company mainly produces silane-based pharmaceutical raw materials and pharmaceutical intermediates  

1,1,1,3,3,3-Hexamethyldisilazane

Product Type  Pharmaceutical Customized Synthesis
Detail  
Product name: 1,1,1,3,3,3-Hexamethyldisilazane
CAS RN:  999-97-3 
SAFETY DATA SHEET:
1、HAZARDS IDENTIFICATION
Classification of the substance or mixture PHYSICAL HAZARDS

 Flammable liquids Category 2 

HEALTH HAZARDS

 Acute toxicity (Oral) Category 4

Acute toxicity (Dermal) Category 3

Acute toxicity (Inhalation) Category 3

Skin corrosion/irritation Category 1B

Serious eye damage/eye irritation Category 1

Specific target organ toxicity - Single exposure [Category 1]

Nervous system Specific target organ toxicity - Single exposure [Category 3]

Respiratory tract irritation, Narcotic effects 

ENVIRONMENTAL HAZARDS

Acute aquatic hazard Category 3 

Long-term aquatic hazard Category 3 

Label elements Pictograms or hazard symbols
Signal word Danger
Hazard statements

Highly flammable liquid and vapour

Harmful if swallowed

Toxic in contact with skin or if inhaled

Causes severe skin burns and eye damage

Causes damage to organs : Nervous system

May cause respiratory irritation

May cause drowsiness or dizziness

Harmful to aquatic life

Harmful to aquatic life with long lasting effects

 Precautionary statements
  [Prevention]

 Keep away from heat, sparks, open flames and hot surfaces. -No smoking.

Keep container tightly closed.

Ground and bond container and receiving equipment.

Use explosion-proof electrical, ventilating and lighting equipment. Use only non-sparking tools. Take precautionary measures against static discharge.

Do not breathe mist, vapors or spray.

Use only outdoors or in a well-ventilated area.

Avoid release to the environment.

Do not eat, drink or smoke when using this product.

Wash hands and face thoroughly after handling.

Wear protective gloves, protective clothing, face protection.

 

 [Response]

IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately call a POISON CENTER or doctor.

IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower. Immediately call a POISON CENTER or doctor. Wash contaminated clothing before reuse.

IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER or doctor.

IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor. If exposed or concerned: Call a POISON CENTER or doctor. In case of fire: Use dry chemical, dry sand or foam to extinguish. 

 [Storage]

Store in a well-ventilated place. Keep container tightly closed.

Store locked up.

 [Disposal] Dispose of contents and container in accordance with local, regional, national regulations.
2、COMPOSITION/INFORMATION ON INGREDIENTS

Substance/mixture: Substance

Components: 1,1,1,3,3,3-Hexamethyldisilazane

Percent: >96.0%(GC)

CAS RN: 999-97-3

Synonyms: HMDS

Chemical Formula: C6H19NSi2

3、 PHYSICAL AND CHEMICAL PROPERTIES

Physical state (20°C): Liquid

Form: Clear

Colour: Colorless  - Almost colorless

Odour: Ammoniacal

pH: No data available

Melting point/freezing point: No data available

Boiling point/range: 126°C Flash point: 8°C

Flammability or explosive limits:   

Lower: 0.8%   

Upper: 16.3%

Vapour pressure: 1.8kPa/25°C

Relative density: 0.77 Solubility(ies):   

[Water] No data available

[Other solvents]    Miscible: Ether, Benzene

Log Pow: 2.62

Autoignition temperature: 380°C

4、STABILITY AND REACTIVITY

Chemical stability: Stable under proper conditions.

Possibility of hazardous reactions: No special reactivity has been reported.

Conditions to avoid:  Spark, Open flame, Static discharge Incompatible materials: Oxidizing agents, Strong acids

Hazardous decomposition products: Carbon monoxide, carbon dioxide etc

 

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