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  The company mainly produces silane-based pharmaceutical raw materials and pharmaceutical intermediates  

tert-Butyldimethylchlorosilane

Product Type  Pharmaceutical Customized Synthesis
Detail  
Product name: tert-Butyldimethylchlorosilane
CAS RN:  18162-48-6
SAFETY DATA SHEET:
1、HAZARDS IDENTIFICATION
Classification of the substance or mixture PHYSICAL HAZARDS

Flammable solids Category 1

HEALTH HAZARDS

 Skin corrosion/irritation Category 1B
 Serious eye damage/eye irritation Category 1

ENVIRONMENTAL HAZARDS

 Not classified

Label elements Pictograms or hazard symbols
Signal word Danger
Hazard statements

Flammable solid
Causes severe skin burns and eye damage

 Precautionary statements
  [Prevention]

Keep away from heat, sparks, open flames and hot surfaces. -No smoking.
Ground and bond container and receiving equipment.
Use explosion-proof electrical, ventilating and lighting equipment.
Do not breathe dusts or mists.
Wash hands and face thoroughly after handling.
Wear protective gloves, protective clothing, face protection.

 [Response]

IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately call a
POISON CENTER or doctor.
IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin
with water or shower. Immediately call a POISON CENTER or doctor. Wash
contaminated clothing before reuse.
IF INHALED: Remove person to fresh air and keep comfortable for breathing.
Immediately call a POISON CENTER or doctor.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact
lenses, if present and easy to do. Continue rinsing. Immediately call a POISON
CENTER or doctor.
In case of fire: Use dry chemical, dry sand or foam to extinguish

 [Storage]

Store locked up.

 [Disposal] Dispose of contents and container in accordance with local, regional, national
regulations
2、COMPOSITION/INFORMATION ON INGREDIENTS

Substance/mixture: Substance
Components: tert-Butyldimethylchlorosilane [tert-Butyldimethylsilylating Agent]
Percent: >98.0%(GC)
CAS RN: 18162-48-6
Synonyms: TBDMSCl , TBSCl , tert-Butylchlorodimethylsilane , tert-Butyldimethylsilyl Chloride
Chemical Formula: C6H15ClSi

 

3、 PHYSICAL AND CHEMICAL PROPERTIES

Physical state (20°C): Solid
Form: Crystal - Powder
Colour: White - Almost white
Odour: No data available
pH: No data available
Melting point/freezing point: 88°C
Boiling point/range: 125°C
Flash point: No data available
Flammability or explosive
limits:
 Lower: No data available
 Upper: No data available
Vapour pressure: 2kPa/20°C
Relative density: No data available
Solubility(ies):
 [Water] No data available
 [Other solvents]
 Soluble: Ether, Benzene, Toluene, Dichloromethane
Autoignition temperature: 200°C

4、STABILITY AND REACTIVITY

Chemical stability: Stable under proper conditions.
Possibility of hazardous reactions: Dust explosion possible if in powder or granular form, mixed with air.
Decomposes in contact with water and liberates toxic gases.
Conditions to avoid: Spark, Open flame, Static discharge, Moisture
Incompatible materials: Oxidizing agents
Hazardous decomposition products:Carbon dioxide, Carbon monoxide, Hydrogen chloride, Silicon oxides

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