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  The company mainly produces silane-based pharmaceutical raw materials and pharmaceutical intermediates  

Tetraethyl Orthosilicate

Product Type  Pharmaceutical Customized Synthesis
Detail  
Product name: Tetraethyl Orthosilicate
CAS RN:  78-10-4
SAFETY DATA SHEET:
1、HAZARDS IDENTIFICATION
Classification of the substance or mixture PHYSICAL HAZARDS Flammable liquids Category 3
HEALTH HAZARDS

Acute toxicity (Inhalation) Category 4
Skin corrosion/irritation Category 2
Serious eye damage/eye irritation Category 2A
Specific target organ toxicity
- Single exposure [Category 1]
Blood system
Specific target organ toxicity
- Single exposure [Category 3]
Respiratory tract irritation, Narcotic effects
Specific target organ toxicity
- Repeated exposure [Category 1]
Respiratory system
Specific target organ toxicity
- Repeated exposure [Category 2]
Kidney

ENVIRONMENTAL HAZARDS Not classified
Label elements Pictograms or hazard symbol

Signal word Danger
Hazard statements Flammable liquid and vapour
Harmful if inhaled
Causes skin irritation
Causes serious eye irritation
Causes damage to organs : Blood system
Causes damage to organs through prolonged or repeated
exposure : Respiratory system
May cause damage to organs through prolonged or
repeated exposure : Kidney
May cause respiratory irritation
May cause drowsiness or dizziness
 Precautionary statements
  [Prevention]
Keep away from heat, sparks, open flames and hot surfaces. -No smoking.
Keep container tightly closed.
Ground and bond container and receiving equipment.
Use explosion-proof electrical, ventilating and lighting equipment. Use only
non-sparking tools. Take precautionary measures against static discharge.
Do not breathe mist, vapors or spray.
Use only outdoors or in a well-ventilated area.
Do not eat, drink or smoke when using this product.
Wash hands and face thoroughly after handling.
Wear protective gloves, eye protection.
 [Response] IF ON SKIN: Wash with plenty of water. If skin irritation occurs: Get medical advice
or attention. Take off contaminated clothing and wash it before reuse.
IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call
a POISON CENTER or doctor if you feel unwell.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact
lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get
medical advice or attention.
If exposed or concerned: Call a POISON CENTER or doctor.
In case of fire: Use dry chemical, dry sand or foam to extinguish.
 [Storage] Store in a well-ventilated place. Keep container tightly closed.
Store locked up.
 [Disposal] Dispose of contents and container in accordance with local, regional, national
regulations.
2、COMPOSITION/INFORMATION ON INGREDIENTS Substance/mixture: Substance
Components: Tetraethyl Orthosilicate
Percent: >97.0%(GC)
CAS RN: 78-10-4
Synonyms: TEOS , Tetraethoxysilane
Chemical Formula: C8H20O4Si
3、 PHYSICAL AND CHEMICAL PROPERTIES Physical state (20°C): Liquid
Form: Clear
Colour: Colorless - Almost colorless
Odour: Mild Ester-like
Odour threshold: 17 ppm
pH: No data available
Melting point/freezing point: -82°C
Boiling point/range: 165°C
Flash point: 54°C
Flammability or explosive
limits:
Lower: 1.3%
Upper: 23%
Vapour pressure: 200Pa/20°C
Vapour density: 7.22
Relative density: 0.93
Solubility(ies):
[Water] Very slightly soluble
[Other solvents]
Miscible: Alcohols
Soluble: Ether
Slightly soluble: Benzene
Log Pow: 0.04
4、STABILITY AND REACTIVITY Chemical stability: Stable under proper conditions.
Possibility of hazardous
reactions:
No special reactivity has been reported.
Conditions to avoid: Spark, Open flame, Static discharge
Incompatible materials: Oxidizing agents, Acids, Water
Hazardous decomposition products:Carbon dioxide, Carbon monoxide, Silicon oxides

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